A-1155463 Chemical Structure
Price of A-1155463
We offer a substantial discount on larger orders,
please inquire via firstname.lastname@example.org or Fax: 1-201-884-1288 (USA Fax#)
A-1155463 is a highly potent and selective BCL-XL inhibitor. A-1155463 is substantially more potent against BCL-XL-dependent cell lines relative to WEHI-539, while possessing none of its inherent pharmaceutical liabilities. A-1155463 caused a mechanism-based and reversible thrombocytopenia in mice and inhibited H146 small cell lung cancer xenograft tumor growth in vivo following multiple doses. A-1155463 thus represents an excellent tool molecule for studying BCL-XL biology as well as a productive lead structure for further optimization.
>99 % by HPLC
Room temperature for short term or -20ºC for 3 years.