Product Name:

AEE-788

Request AEE-788
CAT#: A-1105    

Chemical Structure

AEE-788
IUPAC/Chemical name:
(R)-6-(4-((4-ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Price of AEE-788


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Biological Activity

AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE-788 inhibits phosphorylation of EGFR, HER2, and VEGF2, resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. AEE-788 is in clinical trials.
Technical Data

Chemical Formula: C27H32N6
Exact Mass: 440.26885
Molecular Weight: 440.58
CAS#: 497839-62-0
Optical purity: 100% by chiral HPLC
Chemical Purity: >99% by HPLC
Storage Conditions : Room temperature, or -20ºC for 2 year.
AEE-788 MSDS AEE-788 CoA
Reference