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AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE-788 inhibits phosphorylation of EGFR, HER2, and VEGF2, resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. AEE-788 is in clinical trials.
Chemical Formula: C27H32N6
Exact Mass: 440.26885
Molecular Weight: 440.58
Optical purity: 100% by chiral HPLC
Chemical Purity: >99% by HPLC
Storage Conditions : Room temperature, or -20ºC for 2 year.
AEE-788 MSDS AEE-788 CoA