Product Name: AG-120

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CAT#: A-1323


AG-120 Chemical Structure AG-120 chemical structure

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Biological Activity
AG-120 is an IDH1 (isocitrate dehydrogenase) inhibitor. IDH1 inhibitor reverses the effects of a mutated IDH1 in its uncontrolled production of 2-hydroxyglutarate (2-HG). The presence of 2-HG may prevent cell differentiation and promote transformation of cancerous cells.
Technical Data
Purity: >99 % by HPLC, Chiral purity 100%
M.Wt:      582.97
Formula:     C28H22ClF3N6O3
CAS#: 1448347-49-6
Storage Conditions: Room Temperature or -20ºC for 2 years.