Product Name: AGI-6780

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CAT#: A-1328


AGI-6780 Chemical Structure
AGI-6780 chemical structure

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Biological Activity
AGI-6780 is a potent and selective IDH2 inhibitor. AGI-6780 inhibits the tumor-associated mutant IDH2/R140Q. Treatment with AGI-6780 induced differentiation of TF-1 erythroleukemia and primary human acute myelogenous leukemia cells in vitro. Inhibitors targeting mutant IDH2/R140Q could have potential applications as a differentiation therapy for cancer.
Technical Data
Chemical Formula: C21H18F3N3O3S2
M.Wt: 481.51
CAS#: 1432660-47-3
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.


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