Product Name: AMG-232
 CAT#: A-1354

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 Synonym:AMG-232

AMG-232 Chemical Structure
AMG-232 chemical structure


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Biological Activity
AMG-232 (AMG 232) is an extremely potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC50 = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED50 = 9.1 mg/kg), and is currently in clinical evaluations.
Technical Data

Mol. Formula: C28H35Cl2NO5 S
MW: 568.6
CAS#: 1352066-68-2
Purity: >99%
Chiral Purity: 100%
AMG-232 MSDS AMG-232 CoA

Reference







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