Product Name: ARRY-520
 CAT#: A-1305

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 Synonym:ARRY-520

ARRY-520 Chemical Structure
ARRY-520 chemical structure


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IUPAC/Chemical name:

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Biological Activity
ARRY-520 is a Kinesin Spindle Protein (KSP) inhibitor which has sub-nanomolar potency in both enzymatic and cellular assays and is anti-mitotic, leading to cancer cell death. In vivo, ARRY-520 caused marked tumor regression in preclinical models of human cancer at tolerated doses, often leading to durable responses. ARRY-520 is highly soluble and can be delivered intravenously without requiring enabling formulations.
Technical Data

ARRY-520 MSDS ARRY-520 CoA

Reference







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