Product Name: ASP-5878

Request ASP-5878

CAT#: A-6093


  Synonym:ASP-5878,

ASP-5878 Chemical Structure ASP-5878 chemical structure


IUPAC/Chemical name:


Price of ASP-5878

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Biological Activity
ASP-5878 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR), with potential antineoplastic activity. Upon oral administration, FGFR inhibitor ASP-5878 binds to and inhibits FGFR, which results in the inhibition of FGFR-mediated signal transduction pathways. This inhibits proliferation in FGFR-overexpressing tumor cells. FGFR, a family of receptor tyrosine kinases upregulated in many tumor cell types, plays a key role in cellular proliferation and survival.
Technical Data
M.Wt:     
Formula:    
CAS#:
Purity: > 99% by HPLC
Storage Conditions: Room temperature for months, or -20ºC for 3 years.

Reference