Product Name: AZD-6094(HMPL-504 Volitinib)
AZD-6094 Chemical Structure
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Volitinib (HMPL-504/AZD6094) is a potent small molecule c-Met kinase inhibitor with IC50s in low nanomolar range at enzyme and cell levels. It was found to be highly selective in a screen against a broad panel of kinases. Volitinib has favourable pharmacokinetic properties and demonstrated strong anti-tumor activity in various human xenograft models harbouring c-Met gene amplification and/or protein over-expression.
Solubility:Soluble in DMSO
Storage Conditions: Room temperature, or -20ºC for 3 years.
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