Product Name: BAY87-2243
 CAT#: A-1178

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BAY87-2243 Chemical Structure
BAY87-2243 chemical structure

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Biological Activity
BAY87-2243 is a small molecule inhibitor of hypoxia-induced HIF-1 activation, showed promising anti-tumor efficacy in combination with anti-angiogenic therapy and irradiation in preclinical tumor models. The preclinical results suggest that inhibition of HIF-1 by BAY 87-2243 in particular in combination with anti-angiogenic therapy and irradiation is an innovative approach to cancer therapy with the potential to overcome hypoxia/HIF-induced tumor resistance mechanisms.
Technical Data

Mol. Formula: C26H26F3N7O2
MW: 525.54
CAS#: 1227158-85-1
Purity: >98%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
BAY87-2243 MSDS BAY87-2243 CoA


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