Product Name: BAY87-2243
BAY87-2243 Chemical Structure
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BAY87-2243 is a small molecule inhibitor of hypoxia-induced HIF-1 activation, showed promising anti-tumor efficacy in combination with anti-angiogenic therapy and irradiation in preclinical tumor models. The preclinical results suggest that inhibition of HIF-1 by BAY 87-2243 in particular in combination with anti-angiogenic therapy and irradiation is an innovative approach to cancer therapy with the potential to overcome hypoxia/HIF-induced tumor resistance mechanisms.
Mol. Formula: C26H26F3N7O2
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
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