Product Name:  BMS-906024  Request
CAT#: A-1401    

Chemical Structure

BMS-906024 structure

Price of BMS-906024


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Biological Activity

BMS-906024 is a pan Notch inhibitor. BMS-906024 is a novel, potent Notch receptor inhibitor. Cancers have a tendency to relapse or to become resistant to treatments that once worked. A family of proteins called Notch is implicated in that resistance and in cancer progression more generally. BMS-906024 is in Phase I clinical trials, both alone and in combination with other agents. Patients with colon, lung, breast, and other cancers are receiving intravenous doses of the compound to determine its safety and optimum dose ranges.
Technical Data

M.Wt: 556.50
Formula: C26H26F6N4O3
CAS#: 1401066-79-2
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
Reference