Product Name:


CAT#: A-1160    

Chemical Structure

IUPAC/Chemical name:
(S)-(R)-1-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)propan-2-yl 2-aminopropanoate

Price of Brivanib(BMS-582664)

We offer a substantial discount on larger orders,
please inquire via
or Fax: 1-201-884-1288

We match the lowest price on market.

Biological Activity

Brivanib(BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.
Technical Data

Formula: C22H24FN5O4
M.Wt: 441.46
CAS No.: 649735-63-7
Solubility: DMSO
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 2 years.
1. Discovery of Brivanib Alaninate((S)-((R)-1-(4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), A Novel Prodrug of Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinase Inhibitor (BMS-540215)
J. Med. Chem., 2008, 51 (6), pp 1976ĘC1980
2. Brivanib Alaninate, a Dual Inhibitor of Vascular Endothelial Growth Factor Receptor and Fibroblast Growth Factor Receptor Tyrosine Kinases, Induces Growth Inhibition in Mouse Models of Human Hepatocellular Carcinoma