Docetaxel( Purity > 99% by HPLC)

Product Name: Docetaxel
 CAT#: A-1914

Request Docetaxel
 Synonym: Code name: RP-56976; RP 56976; RP56976. US brand name: Taxotere; Abbreviation: TXT. ,

Docetaxel Chemical Structure
Docetaxelchemical structure

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IUPAC/Chemical name:

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Biological Activity
Docetaxel, also known as RP-56976, is a semi-synthetic, second-generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and cell death. This agent also inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and displays immunomodulatory and pro-inflammatory properties by inducing various mediators of the inflammatory response. Docetaxel has been studied for use as a radiation-sensitizing agent.
Technical Data

Purity: >99%
CAS#:114977-28-5
Chemical Formula:C43H53NO14
Molecular Weight:807.8
Docetaxel MSDSDocetaxel CoA

IUPAC/Chemical name:(2aR,4S,4aS,6R,9S,11S,12S,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate.
Canonical SMILES:
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