Price of GDC-0980
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Biological ActivityGDC-0980 is designed to be a selective, dual inhibitor of PI3 Kinase and mTOR Kinase. PI3 Kinase is an oncogene that is commonly mutated in cancer.
Technical DataFormula: C23H30N8O3S
Optical purity: 100% by chiral HPLC
Chemical Purity: >99% by HPLC
Storage Conditions :Room temperature, or -20ºC for 2 year.
ReferenceA first-in-human, phase l study to evaluate the dual PI3K/mTOR inhibitor GDC-0980 administered QD in patients with advanced solid tumors or non- ˇ
S Dolly, AJ Wagner, JC Bendell, Y Yan, JA Wareˇ - J Clin Oncol (Meeting ˇ, 2010
Combination therapy of the novel PI3K inhibitor GDC-0941 and dual PI3K/mTOR inhibitor (GDC-0980) with trastuzumab-DM1 antibody drug conjugate ˇ
D Sampath, C Fields, G Li - Cancer Res, 2010