Product Name: H-1152

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CAT#: A-1293

  Synonym:; H-1152;

H-1152 Chemical Structure H-1152 chemical structure

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IUPAC/Chemical name:

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Biological Activity

Rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats.

Technical Data
M.Wt:      319.42
Formula:     C16H21 N3 O2 S
CAS#:     451462-58-1
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 2 years.