Product Name: IPI-145
Synonym:IPI145; IPI 145; IPI-145. INK-1197; INK 1197; INK1197
IPI-145 Chemical Structure
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IPI-145 is a potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma.
The PI3K-delta and PI3K-gamma isoforms are preferentially expressed in leukocytes (white blood cells), where they have distinct and non-overlapping roles in key cellular functions, including cell proliferation, cell differentiation, cell migration and immunity. Targeting PI3K-delta and PI3K-gamma may provide multiple opportunities to develop differentiated therapies for the treatment of blood cancers and inflammatory diseases.
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
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