Product Name: Idarubicin Hcl
 CAT#: A-1296

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 Synonym:Idarubicin Hcl

Idarubicin Hcl Chemical Structure
Idarubicin Hcl chemical structure


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Biological Activity
Idarubicin Hydrochloride is the hydrochloride salt preparation of Idarubicin (IDA) (sc-204774), an anthracycline and an analog of daunorubicin (sc-218089). IDA is rapidly metabolized to its 13-dihydroderivative (Idarubicinol) which is more stable than the parent form. This compound has been reported to trigger apoptotic cell death via enhancement of Fas and caspase-3/caspase-7 expression. In experiments, where cells were exposed to IDA, reactive oxygen species (ROS) were produced which induced DNA strand breaks and prevented DNA polymerase reaction.
Technical Data

Mol. Formula: C26H27NO9.HCl
MW: 533.97
CAS#: 57852-57-0
Purity: >99%
Idarubicin Hcl MSDS Idarubicin Hcl CoA

Reference







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