Product Name: LEQ-506

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CAT#: A-1276


  Synonym:LEQ-506,LEQ506

LEQ-506 Chemical Structure
LEQ-506 chemical structure


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Biological Activity
LEQ506 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair.
Technical Data
Chemical Formula: C27H29N5O
M.Wt: 439.55
CAS: 1057677-92-5
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.

Reference




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