Product Name: MK-0731
 CAT#: A-1298

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 Synonym:MK0731

MK-0731 Chemical Structure
MK-0731 chemical structure


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IUPAC/Chemical name: (5S)-3-(2,5-difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-5-(hydroxymethyl)-N-methyl-5-phenyl-2H-pyrrole-1-carboxamide

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Biological Activity
MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.
Technical Data

Mol. Formula: C25H28F3N3O2
MW: 459.21
CAS#: 845256-65-7
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
MK-0731 MSDS MK-0731 CoA

Reference







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