Product Name: Alisertib(MLN-8237)
 CAT#: A-1123

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 Synonym:MLN-8237 ,

MLN-8237 Chemical Structure
MLN-8237chemical structure

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IUPAC/Chemical name:

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Biological Activity
MLN8237 (Alisertib) is a second-generation, selective AAK inhibitor
Alisertib, also known as MLN8237, is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
Technical Data

Purity: >99%
Chemical Formula:C27H20ClFN4O4
Molecular Weight:518.9
MLN-8237 MSDSMLN-8237 CoA

IUPAC/Chemical name:4-((9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-yl)amino)-2-methoxybenzoic acid
Canonical SMILES:O=C(O)C1=CC=C(NC2=NC=C3C(C4=CC=C(Cl)C=C4C(C5=C(OC)C=CC=C5F)=NC3)=N2)C=C1OC

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