Product Name: Alisertib(MLN-8237)Request Alisertib(MLN-8237)
MLN-8237 Chemical Structure
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MLN8237 (Alisertib) is a second-generation, selective AAK inhibitor
Alisertib, also known as MLN8237, is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
MLN-8237 MSDSMLN-8237 CoA
IUPAC/Chemical name:4-((9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[c]pyrimido[4,5-e]azepin-2-yl)amino)-2-methoxybenzoic acid
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