Omecamtiv mecarbil(CK-1827452)( Purity > 99% by HPLC)

Product Name: Omecamtiv mecarbil(CK-1827452)
 CAT#: A-1956

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 Synonym:Omecamtiv mecarbil; CK-1827452; CK 1827452; CK1827452 ,

Omecamtiv mecarbil(CK-1827452) Chemical Structure
Omecamtiv mecarbil(CK-1827452)chemical structure

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IUPAC/Chemical name:

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Biological Activity
Omecamtiv mecarbil, also known as CK-1827452, is a cardiac specific myosin activator. It is clinically tested for its role in the treatment of left ventricular systolic heart failure. Omecamtiv Mecarbil specifically targets and activates myocardial ATPase and improves energy utilization. Omecamtiv Mecarbil improves systolic function by increasing the systolic ejection duration/stroke volume, without consuming more ATP energy, oxygen or altering intracellular calcium levels causing an overall improvement in cardiac efficiency.
Technical Data

Purity: >99%
CAS#:873697-71-3
Chemical Formula:C20H24FN5O3
Molecular Weight:401.43
Omecamtiv mecarbil(CK-1827452) MSDSOmecamtiv mecarbil(CK-1827452) CoA

IUPAC/Chemical name:methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate
Canonical SMILES:O=C(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)OC
Reference





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