Product Name:  Poziotinib  Request Poziotinib
CAT#: A-1363    

Chemical Structure
Poziotinib chemical structure

Price of Poziotinib


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Biological Activity

Poziotinib, also known as HM781-36B and NOV120101, is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity. HM781-36B irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. EGFRs, cell surface receptor tyrosine kinases, are often upregulated in a variety of cancer cell types and play key roles in cellular proliferation and survival.
Technical Data

Formula : C23H21Cl2FN4O3
CAS# : 1092364-38-9
M.Wt: 491.34
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
Reference








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