Product Name: RS-102895 HClRequest RS 102895 hydrochloride
RS 102895 hydrochloride Chemical Structure
5 stars, based on 1836 reviewsIUPAC/Chemical name:
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Biological ActivityCCR2-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Also inhibits α1A, α1D and 5-HT1A receptors.
IUPAC/Chemical name:1'-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one hydrochloride
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