Product Name: RX-3117 Request RX-3117
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RX-3117, also known as TV-1360 and fluorocyclopentenylcytosine, is a potent DNA synthesis inhibitor. RX-3117 belongs to the class of cytotoxic antimetabolite nucleoside compounds. In vitro and in vivo studies have demonstrated successful preliminary efficacy and therapeutic potential. RX-3117 interferes with enzymes or metabolites responsible for the process of cell division, nucleic acid synthesis, arrests cells in G1 phase and induces apoptosis. RX-3117 also inhibits cdc2 kinase and DNMT-1 protein expression, which are further involved in cell division processes. RX-3117 is activated by uridine-cytidine kinase and is activated by a mechanism different from that of gemcitabine.
Formula : C10H12FN3O4
CAS# : 865838-26-2
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.
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