Product Name:  Rocaglamide  Request Rocaglamide
CAT#: A-1624    

Chemical Structure
Rocaglamide structure

Price of Rocaglamide


We offer a substantial discount on larger orders,
please inquire via sales@activebiochem.com
or Fax: 1-201-884-1288
Biological Activity

Rocaglamide is an immunosuppressant, and a potent inhibitor of NF-κB activation in T cells, with an almost complete inhibition at 200nM. Suppresses cytokine production (IFN-γ, TNF-α, IL-2 and IL-4) and inhibits NF-AT in peripheral blood T cells at concentrations that do not impair NF-κB and AP-1 activities.
Technical Data

Molecular Formula: C29H31NO7
Molecular Weight: 505.57
CAS #: 84573-16-0
Solubility: Soluble in DMSO, 100% ethanol or methanol.
Long Term Storage: -20ºC for 3 years.
SMILES
CN(C)C(=O)C1C(C2(C(C1O)(C3=C(C=C(C=C3O2)OC)OC)O)C4=CC=C(C=C4)OC)C5=CC= CC=C5
IUPAC/Chemical name
(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Reference