Product Name:  SCH-900776  Request SCH-900776
CAT#: A-1202

Chemical Structure

SCH-900776 chemical structure

Price of SCH-900776


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Biological Activity

SCH 900776 is a potent and selective CHK1 inhibitor with IC50 of 3 nM, 0.16 and 1.5 uM for CHK1, CDK2 and CHK2, respectively.
Technical Data
Formula:    C15H18BrN7
M.Wt:     376.25
CAS#:     891494-63-6
Solubility : DMSO
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 2 years.
SCH-900776 MSDS SCH-900776 CoA
Reference

Preclinical Development of the Novel Chk1 Inhibitor SCH900776 in Combination with DNA-Damaging Agents and Antimetabolites
...SCH900776 is a novel and more selective Chk1 inhibitor that potently inhibits Chk1 and abrogates cell-cycle arrest induced by SN38...SCH900776 is currently in phase I clinical trials, and these result provide the rationale and schedule for futrue clinical trials...