Product Name:


CAT#: A-1060    

Chemical Structure


Price of SGX-523

5MG $190
10MG $280
20MG $450
50MG $780
We offer a substantial discount on larger orders,
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Biological Activity

An orally bioavailable small molecule, belonging to the class of c-Met/hepatocyte growth factor receptor (HGFR) tyrosine kinase inhibitors, with potential antineoplastic activity. MET receptor tyrosine kinase inhibitor SGX523 specifically binds to c-Met protein, or hepatocyte growth factor receptor (HGFR), preventing binding of hepatocyte growth factor (HGF) and disrupting the MET signaling pathway; this agent may induce cell death in tumor cells expressing c-Met. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays an important role in tumor cell proliferation, survival, invasion, and metastasis, and in tumor angiogenesis.
Technical Data

M.Wt: 359.41
CAS #:1022150-57-7
Storage Conditions :Room temperature, or -20ºC for 2 year.