Product Name:  SR-13668  Request
CAT#: A-1206    

Chemical Structure

Price

We offer a substantial discount on larger orders,
please inquire via sales@activebiochem.com
or Fax: 1-201-884-1288
Biological Activity

SR13668, an orally active Akt/PKB pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies.
Technical Data

Formula:C25H22N2O5
M.Wt:430.45
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 2 years.
IUPAC Name: diethyl 6-methoxy-5,7-dihydroindolo[2,3-b]carbazole-2,10-dicarboxylate
Reference

1. Phase 0 Clinical Chemoprevention Trial of the Akt Inhibitor SR13668
http://cancerpreventionresearch.aacrjournals.org/content/4/3/347
SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. To accelerate the clinical development of this promising agent, we designed and conducted the first-ever phase 0 chemoprevention trial to evaluate and compare the effects of food and formulation on SR13668 bioavailability....