Product Name: SR-13668 Request
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SR13668, an orally active Akt/PKB pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies.
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 2 years.
IUPAC Name: diethyl 6-methoxy-5,7-dihydroindolo[2,3-b]carbazole-2,10-dicarboxylate
1. Phase 0 Clinical Chemoprevention Trial of the Akt Inhibitor SR13668
SR13668, an orally active Akt pathway inhibitor, has demonstrated cancer chemopreventive potential in preclinical studies. To accelerate the clinical development of this promising agent, we designed and conducted the first-ever phase 0 chemoprevention trial to evaluate and compare the effects of food and formulation on SR13668 bioavailability....