Product Name: Semagacestat (LY450139)
 CAT#: A-1952

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Semagacestat (LY450139) Chemical Structure
Semagacestat (LY450139) chemical structure


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Biological Activity
Semagacestat (LY450139) is an blocker of γ-secretase for Aβ42, Aβ40 and Aβ38 with IC50 of 10.9 nM, 12.1 nM and 12.0 nM, also inhibits Notch signaling with IC50 of 14.1 nM.
Technical Data

CAS#: 425386-60-3
Chemical Formula:C19H27N3O4
M.Wt.:361.44
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 3 years.

Reference







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