Product Name: VX-11e
 CAT#: A-1195

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 Synonym:VX-11e,

VX-11e Chemical Structure
VX-11e chemical structure


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IUPAC/Chemical name:

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Biological Activity
VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK2 ( Ki < 2 nM) which exhibits potent cellular activity with IC50=48 nM in HT29 cell line. It is highly selective against a panel of more than 140 other kinases, such as GSK3 (Ki = 400nM), AURA (Ki = 540nM), CDK2 (Ki = 850nM), FLT3 (Ki = 1400nM), ROCK1 (Ki = 1400nM), and JNK3 (Ki = 1400nM)
Technical Data

Formula: C24H21Cl2FN5O2
MW: 501.36
Purity: >99%
Chiral purity : 100%
VX-11e MSDS VX-11e CoA

Reference







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