Product Name:

TAK-700

Request TAK-700
CAT#: A-1193    

Chemical Structure tak-700
IUPAC/Chemical name:
6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide

Price of TAK-700

Index Size Price
1 5mg $380
2 10mg $580
3 20mg $880
4 50mg $1,200
We offer a substantial discount on larger orders,
please inquire via sales@activebiochem.com
or Fax: 1-201-884-1288(USA Fax#)

We match the lowest price on market.

Biological Activity

TAK-700 is an oral, selective, non-steroidal androgen synthesis inhibitor of the 17,20 lyase in clinical trials.
Technical Data
Formula:    C18H17N3O2
M.Wt:     307.13
CAS#:     426219-23-0 (free base), 426219-53-6 (salt)
Purity: >99%
Storage Conditions: 2ºC to 8 ºC, or -20ºC for 2 years.
Reference
Novel therapeutic strategies for castration resistant prostate cancer: inhibition of persistent androgen production and androgen receptor mediated signaling
A Molina...- The Journal of urology, 2011 - Elsevier
... with progression after docetaxel based chemotherapy. TAK-700 and TOK-001 (formerly VN124-1) are novel selective cytochrome p450 17 inhibitors that recently entered phase I/II evaluation. MDV3100 is a second generation ...

Targeting continued androgen receptor signaling in prostate cancer
C Massard... - Clinical Cancer Research, 2011 - AACR
clincancerres.aacrjournals.org
... Several novel agents also targeting androgen receptor signaling are currently being evaluated, including MDV3100 and orteronel (TAK-700). ... Other Drugs. TAK-700 (Orteronel). TAK-700 is a selective, but less potent, nonsteroidal inhibitor of 17,20-lyase. ...