Aclarubicin Hydrochloride( Purity > 99% by HPLC)

Product Name: Aclarubicin Hydrochloride
 CAT#: A-2023

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 Synonym:aclacinomycin; Aclacinomycin A; Aclacinomycin A hydrochloride; aclacinomycin-A; Aclarubicin Hydrochloride; Antibiotic MA144-A1. Foreign brand names: Aclacin; Aclacinomycine; Aclacinon; Aclaplastin; Ja ,

Aclarubicin Hydrochloride Chemical Structure
Aclarubicin Hydrochloridechemical structure

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IUPAC/Chemical name:

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Biological Activity
Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin.
Technical Data

Purity: >99%
CAS#:75443-99-1
Chemical Formula:C42H54ClNO15
Molecular Weight:848.33l
Aclarubicin Hydrochloride MSDSAclarubicin Hydrochloride CoA

IUPAC/Chemical name:(1R,2R,4S)-methyl 4-(((2R,5S,6S)-4-(dimethylamino)-5-(((2S,4S,5S,6S)-4-hydroxy-6-methyl-5-(((2R,6S)-6-methyl-5-oxotetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate hydrochloride
Canonical SMILES:
Reference





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