Amifostine( Purity > 99% by HPLC)

Product Name: Amifostine
 CAT#: A-2029

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 Synonym:Aminopropylaminoethylthiophosphoric Acid; ethiofos; gammaphos. US brand name: Ethyol. Abbreviation: APAETP. Code names: WR-2721; YM-08310. ,

Amifostine Chemical Structure
Amifostinechemical structure

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IUPAC/Chemical name:

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Biological Activity
Amifostine is a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite, the thiol metabolite binds to and detoxifies cytotoxic platinum-containing metabolites of cisplatin and scavenges free radicals induced by cisplatin and ionizing radiation. The elevated activity of this agent in normal tissues results from both the relative abundance of alkaline phosphatase in normal tissues and the greater vascularity of normal tissues compared to tumor tissues
Technical Data

Purity: >99%
CAS#: 112901-68-5
Chemical Formula:C5H21N2O6PS
Molecular Weight:268.27
Amifostine MSDSAmifostine CoA

IUPAC/Chemical name:S-(2-((3-aminopropyl)amino)ethyl) O,O-dihydrogen phosphorothioate trihydrate
Canonical SMILES:
Reference





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