Amrubicin( Purity > 99% by HPLC)

Product Name: Amrubicin
 CAT#: A-2032

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 Synonym: Amirubicin Hydrochloride. Foreign brand name: Calsed. Abbreviation: AMR. ,

Amrubicin Chemical Structure
Amrubicinchemical structure

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IUPAC/Chemical name:

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Biological Activity
Amrubicin hydrochloride is the hydrochloride salt of a third-generation synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in inhibition of DNA replication, and RNA and protein synthesis, followed by cell growth inhibition and cell death. This agent has demonstrated a higher level of anti-tumor activity than conventional anthracycline drugs without exhibiting any indication of the cumulative cardiac toxicity common to this class of compounds. It is marketed in Japan since 2002 by Sumitomo Pharmaceuticals.
Technical Data

Purity: >99%
CAS#:110267-81-7
Chemical Formula:C25H25NO9
Molecular Weight:483.47
Amrubicin MSDSAmrubicin CoA

IUPAC/Chemical name:(7S,9S)-9-acetyl-9-amino-7-(((2S,4S,5R)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6,11-dihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride
Canonical SMILES:
Reference





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