Aprepitant( Purity > 99% by HPLC)

Product Name: Aprepitant
 CAT#: A-2035

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 Synonym: US brand name: Emend; Code names: L-754030; MK-0869; ONO-7436. ,

Aprepitant Chemical Structure
Aprepitantchemical structure

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IUPAC/Chemical name:

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Biological Activity
Aprepitant is a small molecule, high-affinity substance P antagonist (SPA) with antiemetic activity. Crossing the blood brain barrier, aprepitant binds selectively to the human substance P/neurokinin 1 receptor in the central nervous system (CNS), thereby inhibiting receptor binding of endogenous substance P and substance P-induced emesis. This agent has little or no affinity for serotonin type 3 (5-HT3), dopamine, and corticosteroid receptors.
Technical Data

Purity: >99%
Chemical Formula:C23H21F7N4O3
Molecular Weight:534.43
Aprepitant MSDSAprepitant CoA

IUPAC/Chemical name:5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one
Canonical SMILES:

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