Azacitidine( Purity > 99% by HPLC)

Product Name: Azacitidine
 CAT#: A-2036

Request Azacitidine
 Synonym: 5-AC; 5-azacytidine; azacytidine; ladakamycin. US brand names: Mylosar; Vidaza. Abbreviations: 5-AC; 5-AZC. Code name: U-18496. ,

Azacitidine Chemical Structure
Azacitidinechemical structure

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IUPAC/Chemical name:

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Biological Activity
Azacitidine is a pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA methyltransferase, thereby blocking DNA methylation. Hypomethylation of DNA by azacitidine may activate tumor suppressor genes silenced by hypermethylation, resulting in an antitumor effect. This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity.
Technical Data

Purity: >99%
CAS#:320-67-2
Chemical Formula:C8H12N4O5
Molecular Weight:244.2
Azacitidine MSDSAzacitidine CoA

IUPAC/Chemical name:4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
Canonical SMILES:
Reference





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