Product Name: Azathioprine SodiumRequest Azathioprine Sodium
Synonym: US brand name: Imuran. Foreign brand name: Imurel. Abbreviations: AZA. ,
Azathioprine Sodium Chemical Structure
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Biological Activityazathioprine sodium is the sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substitutes for the normal nucleoside and mistakenly gets incorporated into DNA sequences. This leads to inhibition of DNA, RNA, and protein synthesis. As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes.
IUPAC/Chemical name:6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-7H-purine sodium
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