Belinostat( Purity > 99% by HPLC)

Product Name: Belinostat
 CAT#: A-2039

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 Synonym: PXD 101; PXD-101; PXD101; NSC726630; PX-105684; brand name: Beleodaq. ,

Belinostat Chemical Structure
Belinostatchemical structure

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IUPAC/Chemical name:

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Biological Activity
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase. Belinostat was approved in 2014 for relapsed or refractory peripheral T-cell lymphoma.
Technical Data

Purity: >99%
CAS#:414864-00-9
Chemical Formula:C15H14N2O4S
Molecular Weight:318.34
Belinostat MSDSBelinostat CoA

IUPAC/Chemical name:(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide.
Canonical SMILES:
Reference





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