Product Name: CisplatinRequest Cisplatin
Synonym: CACP; cis-DDP; cis-diamminedichloro platinum (II); cis-diamminedichloroplatinum; Cis-dichloroammine Platinum (II); Cismaplat; Cisplatina; cis-platinous diamine dichloride; cis-platinum; cis-platinum ,
Cisplatin Chemical Structure
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Biological ActivityCisplatin is an inorganic platinum agent (cis-diamminedichloroplatinum) with antineoplastic activity. Cisplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups such as GC-rich sites in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in apoptosis and cell growth inhibition.
IUPAC/Chemical name:(SP-4-2)-diamminedichloroplatinum; platinum, diaminedichloro-, cis- (8CI).
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