Cladribine( Purity > 99% by HPLC)

Product Name: Cladribine
 CAT#: A-2061

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 Synonym: Cladribina. US brand name: Leustatin. Foreign brand names: Leustat; Leustatine. Abbreviations: 2CDA; 2-CdA. Code name: RWJ-26251. Chemical structure names: * 2-chloro-2-deoxyadenosine; * 2-chlorodeox ,

Cladribine Chemical Structure
Cladribinechemical structure

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IUPAC/Chemical name:

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Biological Activity
Cladribine is a purine nucleoside antimetabolite analogue. Cladribine triphosphate, a phosphorylated metabolite of cladribine, incorporates into DNA, resulting in single-strand breaks in DNA, depletion of nicotinamide adenine dinucleotide (NAD) and adenosine triphosphate (ATP), and apoptosis. Because this agent is resistant to adenosine deaminase, an enzyme that inactivates some antineoplastic agents, it is selectively toxic to lymphocytes and monocytes which exhibit little deoxynucleotide deaminase activity.
Technical Data

Purity: >99%
CAS#:4291-63-8
Chemical Formula:C10H12ClN5O3
Molecular Weight:285.69
Cladribine MSDSCladribine CoA

IUPAC/Chemical name:(2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Canonical SMILES:
Reference





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