Dactinomycin (Actinomycin D)( Purity > 99% by HPLC)

Product Name: Dactinomycin (Actinomycin D)
 CAT#: A-2069

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 Synonym:Abbreviation: DACT; ACT-D; actinomycin C1; actinomycin D; actinomycin I1; actinomycin IV; actinomycin X 1; actinomycin-[thr-val-pro-sar-meval]; dactinomycine; meractinomycin; US brand names: Cosmeg ,

Dactinomycin (Actinomycin D) Chemical Structure
Dactinomycin (Actinomycin D)chemical structure

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IUPAC/Chemical name:

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Biological Activity
Dactinomycin (also known generically as Actinomycin D ) is the most significant member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. As one of the older chemotherapy drugs, it has been used for many years. Actinomycin D was the first antibiotic shown to have anti-cancer activity. It was first isolated by Selman Waksman and his co-worker H. B. Woodruff in 1940. It was approved by the US FDA on December 10, 1964 and launched by Merck Sharp and Dohme under the trade name Cosmegen.
Technical Data

Purity: >99%
Chemical Formula:C62H86N12O16
Molecular Weight:1255.42
Dactinomycin (Actinomycin D) MSDSDactinomycin (Actinomycin D) CoA

IUPAC/Chemical name: 2-amino-N1,N9-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Canonical SMILES: O=C(C1=C(N)C(C(C)=C2OC3=C(N=C21)C(C(N[C@H](C(N[C@@H](C(N4CCC[C@]4(C(N(CC(N([C@H](C5=O)C(C)C)C)=O)C)=O)[H])=O)C(C)C)=O)[C@H](O5)C)=O)=CC=C3C)=O)N[C@@H]6C(N[C@H](C(C)C)C(N7[C@](CCC7)([H])C(N(C)CC(N(C)[C@@H](C(C)C)C(O[C@@H]6C)=O)=O)=O)=O)=O

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