Product Name: DiaziquoneRequest Diaziquone
Synonym:Aziridinyl Benzoquinone; aziridinylbenzoquinone; Aziridinylbenzoquinone carbamic acid. Abbreviation: AZQ. Code name: CI-904. ,
Diaziquone Chemical Structure
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Biological ActivityDiaziquone is a synthetic bifunctional quinone derivative with potential antineoplastic activity. Diaziquone alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent can also form free radicals, thereby initiating DNA damage via DNA strand breaks. Due to its lipophilicity, diaziquone readily crosses the blood brain barrier.
IUPAC/Chemical name:diethyl (2,5-di(aziridin-1-yl)-3,6-dioxocyclohexa-1,4-diene-1,4-diyl)dicarbamate
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