Doxifluridine( Purity > 99% by HPLC)

Product Name: Doxifluridine
 CAT#: A-2076

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 Synonym: doxifluridine; Furtulon; Flutron; doxyfluridine; 5'-Doxifluridine; Furtulon (TN); 5'-Deoxy-5-fluorouridine; 5-Fluorodeoxyuridine; 5'-Dfur Abbreviation: 5-DFUR. Chemical structure name: 5'-deoxy-5-flu ,

Doxifluridine Chemical Structure
Doxifluridinechemical structure

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IUPAC/Chemical name:

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Biological Activity
Doxifluridine is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.
Technical Data

Purity: >99%
CAS#:3094-09-5
Chemical Formula:C9H11FN2O5
Molecular Weight:246.19
Doxifluridine MSDSDoxifluridine CoA

IUPAC/Chemical name:1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
Canonical SMILES:
Reference





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