Fotemustine( Purity > 99% by HPLC)

Product Name: Fotemustine
 CAT#: A-2101

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 Synonym: Foreign brand name: Muphoran. Code name: S 10036. ,

Fotemustine Chemical Structure
Fotemustinechemical structure

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IUPAC/Chemical name:

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Biological Activity
Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier.
Technical Data

Purity: >99%
CAS#: 92118-27-9
Chemical Formula:C9H19ClN3O5P
Molecular Weight:315.69
Fotemustine MSDSFotemustine CoA

IUPAC/Chemical name:diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate
Canonical SMILES:
Reference





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