Fulvestrant( Purity > 99% by HPLC)

Product Name: Fulvestrant
 CAT#: A-2102

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 Synonym:ZD9238; ZD-9238; ZD 9238; ICI 182,780; ICI-182,780; ICI182,780; ICI182780; ICI 182780; ICI-182780; ZM-182780; ZM 182780; ZM182780; Fulvestrant; US brand name: Faslodex. ,

Fulvestrant Chemical Structure
Fulvestrantchemical structure

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IUPAC/Chemical name:

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Biological Activity
Fulvestrant is a synthetic estrogen receptor antagonist. Unlike tamoxifen (which has partial agonist effects) and the aromatase inhibitors (which reduce the estrogen available to tumor cells), fulvestrant binds competitively to estrogen receptors in breast cancer cells, resulting in estrogen receptor deformation and decreased estrogen binding. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines.
Technical Data

Purity: >99%
CAS#: 129453-61-8
Chemical Formula:C32H47F5O3S
Molecular Weight:606.77
Fulvestrant MSDSFulvestrant CoA

IUPAC/Chemical name:(7R,8R,9S,13S,14S,17S)-13-methyl-7-(9-((4,4,5,5,5-pentafluoropentyl)sulfinyl)nonyl)-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Canonical SMILES: OC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](O)CC[C@@]4([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC2=C1
Reference





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