Product Name: IcotinibRequest Icotinib
Synonym: Icotinib; BPI-2009; BPI 2009; BPI2009; Brand name: Conmana. ,
Icotinib Chemical Structure
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Biological ActivityIcotinib, also known as BPI-2009, is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, is upregulated in a variety of cancer cell types. Icotinib was approved in China in 2011.
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