Lapatinib (Free Base)( Purity > 99% by HPLC)

Product Name: Lapatinib (Free Base)
 CAT#: A-2124

Request Lapatinib (Free Base)
 Synonym:Synonym: Lapatinib. US brand name: Tykerb; Code names: GSK572016 GW2016; GW-572016. ,

Lapatinib (Free Base) Chemical Structure
Lapatinib (Free Base)chemical structure

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IUPAC/Chemical name:

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Biological Activity
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types.
Technical Data

Purity: >99%
CAS#: 231277-92-2
Chemical Formula:C29H26ClFN4O4S
Molecular Weight:581.06
Lapatinib (Free Base) MSDSLapatinib (Free Base) CoA

IUPAC/Chemical name:N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
Canonical SMILES:O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)O1)(C)=O

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