Leucovorin Calcium( Purity > 99% by HPLC)

Product Name: Leucovorin Calcium
 CAT#: A-2128

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 Synonym:calcium (6S)-folinate; calcium folinate; citrovorum factor; folinate calcium; folinic acid; Folinic Acid Calcium Salt Pentahydrate; Leucovorin; LV; US brand name: Wellcovorin Foreign brand names: Adin ,

Leucovorin Calcium Chemical Structure
Leucovorin Calciumchemical structure

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IUPAC/Chemical name:

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Biological Activity
leucovorin calcium is an active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist-type chemotherapeutic drugs. Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist. This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity
Technical Data

Purity: >99%
CAS#:1492-18-8
Chemical Formula:C20H21CaN7O7
Molecular Weight:511.5
Leucovorin Calcium MSDSLeucovorin Calcium CoA

IUPAC/Chemical name:N-[4-[[(2-amino-5-formyl-1, 4, 5, 6, 7, 8-hexahydro-4-oxo-6-pteridinyl)-methyl]amino]benzoyl]-L-glutamic acid calcium salt hydrate
Canonical SMILES:
Reference





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