Methotrexate( Purity > 99% by HPLC)

Product Name: Methotrexate
 CAT#: A-2143

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 Synonym: alpha-methopterin; amethopterin; Methotrexatum; methylaminopterin; Metotrexato. US brand names: Abitrexate; Folex; Folex PFS; Methotrexate LPF; Mexate; Mexate-AQ; Foreign brand names: Brimexate; Emte ,

Methotrexate Chemical Structure
Methotrexatechemical structure

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IUPAC/Chemical name:

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Biological Activity
Methotrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
Technical Data

Purity: >99%
Chemical Formula:C20H22N8O5
Molecular Weight:454.44
Methotrexate MSDSMethotrexate CoA

IUPAC/Chemical name:(S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid.
Canonical SMILES:

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