Product Name: MitotaneRequest Mitotane
Synonym: Chloditan; Chlodithane; Khloditan; Mytotan; o,p'-DDD; Ortho,para-DDD. US brand name: Lysodren. Foreign brand name: Lisodren. Abbreviations: DDD; o,p' - DDD; o,p'-DDD. Code names: CB-313 ,
Mitotane Chemical Structure
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Biological Activity Mitotane is a synthetic derivative of the insecticide dichlorodiphenyl trichloroethane (DDT) with anti-adrenocorticoid properties. Following its metabolism in the adrenal cortex to a reactive acyl chloride intermediate, mitotane covalently binds to adrenal proteins, specifically inhibiting adrenal cortical hormone production.
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