Oxaliplatin( Purity > 99% by HPLC)

Product Name: Oxaliplatin
 CAT#: A-2167

Request Oxaliplatin
 Synonym: diaminocyclohexane oxalatoplatinum; oxalatoplatin; oxalatoplatinum; US brand name: Eloxatin Foreign brand names: Dacotin; Dacplat; Eloxatine; Abbreviations: 1-OHP; L-OHP; Code names: JM-83; RP-54780; ,

Oxaliplatin Chemical Structure
Oxaliplatinchemical structure

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IUPAC/Chemical name:

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Biological Activity
Oxaliplatin is an organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a 'leaving group.' A 'leaving group' is an atom or a group of atoms that is displaced as a stable species taking with it the bonding electrons. After displacement of the labile oxalate ligand leaving group, active oxaliplatin derivatives, such as monoaquo and diaquo DACH platinum, alkylate macromolecules, forming both inter- and intra-strand platinum-DNA crosslinks, which result in inhibition of DNA replication and transcription and cell-cycle nonspecific cytotoxicity. The DACH side chain appears to inhibit alkylating-agent resistance.
Technical Data

Purity: >99%
CAS#:61825-94-3
Chemical Formula:C8H14N2O4Pt
Molecular Weight:397.29
Oxaliplatin MSDSOxaliplatin CoA

IUPAC/Chemical name:[(1R,2R)-cyclohexane-1,2-diamine](ethanedioato-O,O')platinum(II)
Canonical SMILES:
Reference





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